Recombinant CD278/ICOS Monoclonal Antibody

SKU: AN301473L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:CD278/ICOS

Target Synonym:CVID;ICOS;AILIM;CD278;CVID1;activation-inducible lymphocyte immunomediatory molecule;Inducible T-cell costimulator

Research Areas:Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A168

UNIProt ID:Q9Y6W8

Accession:

Background:Enhances all basic T-cell responses to a foreign antigen, namely proliferation, secretion of lymphokines, up-regulation of molecules that mediate cell-cell interaction, and effective help for antibody secretion by B-cells. Essential both for efficient interaction between T and B-cells and for normal antibody responses to T-cell dependent antigens. Does not up-regulate the production of interleukin-2, but superinduces the synthesis of interleukin-10. Prevents the apoptosis of pre-activated T-cells. Plays a critical role in CD40-mediated class switching of immunoglobin isotypes.

Concentration:1 mg/mL

Immunogen:Recombinant human CD278/ICOS fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:IHC 1:200-1:1000

Calculated MW:

ObservedMW: