Recombinant CD11b Monoclonal Antibody

SKU: AN300797L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:CD11b

Target Synonym:MAC;SLEB;Leukocyte adhesion receptor MO;CD11B;CR3A;MAC-1;MAC1A;MO1A;SLEB6;ITGAM;CD11b/ITAM;Integrin alpha-M;CD11 antigen-like family member B;CR-3 alpha chain;Cell surface glycoprotein MAC-1 subunit alpha;Leukocyte adhesion receptor MO1;Neutrophil adherence receptor;integrin &alpha-M-M;antigen CD11b(p170) |integrin alpha M|macrophage antigen alpha polypeptide|neutrophil adherence receptor alpha-M subunit;MGC117044

Research Areas:Signal Transduction;Tags & Cell Markers;Neuroscience;Stem Cells;Immunology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:3G7

UNIProt ID:P11215

Accession:

Background:ITGAM(integrin subunit alpha M) Homo sapiens This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human CD11b protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:127 kDa

ObservedMW:170 kDa