Recombinant Caveolin-1 Monoclonal Antibody

SKU: AN300820L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Caveolin-1

Target Synonym:PPH;CGL;BSCL;MSTP;cell growth-inhibiting protein;OTTHUMP;VIP;BSCL3;CGL3;LCCNS;MSTP085;PPH3;VIP21;CAV1;22 kD;caveolae protein;caveolin 1 alpha isoform;caveolin 1 beta isoform;Caveolin 1 caveolae protein 22kDa;Caveolin1;Caveolin-1;cell growth-inhibiting protein 32;OTTHUMP00000025031;VIP 21;CAV

Research Areas:Cardiovascular;Signal Transduction;Tags & Cell Markers;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:5B4

UNIProt ID:Q03135

Accession:

Background:The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Caveolin-1 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:20 kDa

ObservedMW:20 kDa