Recombinant Caspase-9 Monoclonal Antibody

SKU: AN301044L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:Caspase-9

Target Synonym:MCH;Apoptotic protease Mch;PPP1R;ICE-LAP;CASP9;APAF-3;APAF3;ICE-LAP6;MCH6;PPP1R56;caspase-9;Caspase 9;CASP-9;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3 (APAF-3);ICE-like apoptotic protease 6 (ICE-LAP6);Apoptosis related cysteine peptidase;Apoptotic protease-activating factor 3;Caspase 9 apoptosis related cysteine peptidase;Caspase 9 Dominant Negative;Caspase 9c;Caspase-9 subunit p10;ICE LAP6;ICE like apoptotic protease 6;ICE-like apoptotic protease 6;protein phosphatase 1;regulatory subunit 56;RNCASP9

Research Areas:Cell Biology;Cancer;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6C11

UNIProt ID:P55211

Accession:

Background:This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein can undergo autoproteolytic processing and activation by the apoptosome, a protein complex of cytochrome c and the apoptotic peptidase activating factor 1; this step is thought to be one of the earliest in the caspase activation cascade. This protein is thought to play a central role in apoptosis and to be a tumor suppressor. Alternative splicing results in multiple transcript variants.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human Caspase-9 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:1000-1:5000;IHC 1:500-1:1000

Calculated MW:46 kDa

ObservedMW:40 kDa