Recombinant Bovine TGFBR1 protein (His tag)

SKU: PDEB100010

Size:100μg

Storage:Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.

Shipping:This product is provided as lyophilized powder which is shipped with ice packs.

Exp date:12 months

Category ID_II:Recombinant Proteins

Category ID_III:Others

Abbreviation:TGFBR1

Target Synonym:AAT5;ACVRLK 4;ALK 5;Activin A receptor type II like kinase 53kDa;Activin receptor like kinase 5;LDS1A;MSSE;SKR4;Serine/threonine-protein kinase receptor R4;TGF beta Receptor I;TGFR 1;TbetaR-I

Research Areas:Cardiovascular;Signal Transduction;Stem Cells;Cancer;Metabolism;Neuroscience

Conjugation:

Target Species:Bovine

Expression Host:E.coli

Application:

Fusion tag:N-His

UNIProt ID:O46680

Accession:O46680

Background:On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.

Concentration:

Activity:Not validated for activity

Sequence:Ile 143-Leu 330

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation:Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution:It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin:< 10 EU/mg of the protein as determined by the LAL method.

Calculated MW:20.6 kDa

ObservedMW:20 kDa