Recombinant BMI1 Monoclonal Antibody

SKU: AN300141P

Size::

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies

Abbreviation:BMI1

Target Synonym:RNF;BMI;PCGF;flvi-2/bmi;FLVI2/BMI;BMI1;FLVI2/BMI1;PCGF4;RNF51;flvi-2/bmi-1

Research Areas:Cell Biology;Epigenetics and Nuclear Signaling;Stem Cells;Cancer

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:IHC-P

Isotype:IgG

Clonality:Rabbit Monoclonal

Clone NO.:4B3

UNIProt ID:P35226

Accession:

Background:This gene encodes a ring finger protein that is major component of the polycomb group complex 1 (PRC1). This complex functions through chromatin remodeling as an essential epigenetic repressor of multiple regulatory genes involved in embryonic development and self-renewal in somatic stem cells. This protein also plays a central role in DNA damage repair. This gene is an oncogene and aberrant expression is associated with numerous cancers and is associated with resistance to certain chemotherapies. A pseudogene of this gene is found on chromosome X. Read-through transcription also exists between this gene and the upstream COMM domain containing 3 (COMMD3) gene.

Concentration:1 mg/mL

Immunogen:A synthetic peptide corresponding to the center region of the Human BMI1

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:IHC-P 1:100-1:500;

Calculated MW:

ObservedMW: