Recombinant BMAL1 Monoclonal Antibody

SKU: AN300681L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:BMAL1

Target Synonym:JAP;MOP;MIC;Pgp;CDW;BMAL;PASD;CSPG;bHLHe;MDU;ARNTL;BMAL1;BMAL1c;JAP3;MOP3;PASD3;TIC;bHLHe5;aryl hydrocarbon receptor nuclear translocator like;IN;LHR;MC56;MDU2;MDU3;MIC4;Pgp1;CDW44;CSPG8;HCELL;HUTCH-I;ECMR-III;ARNT like protein 1 brain and muscle;Aryl hydrocarbon receptor nuclear translocator like protein 1;Aryl hydrocarbon receptor nuclear translocator-like protein 1;Basic helix loop helix PAS orphan MOP3;Basic helix loop helix PAS protein MOP3;Basic-helix-loop-helix-PAS protein MOP3;bHLH PAS protein JAP3;bHLH-PAS protein JAP3;BMAL 1;Brain and muscle ARNT like 1;Brain and muscle ARNT-like 1;CG8727 PA;Class E basic helix-loop-helix protein 5;cycle;JAP 3;Member of PAS protein 3;Member of PAS superfamily 3;MGC47515;MOP 3;PAS domain-containing protein 3;PASD 3

Research Areas:Cardiovascular;Epigenetics and Nuclear Signaling;Neuroscience;Metabolism

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:6A2

UNIProt ID:O00327

Accession:

Background:The protein encoded by this gene is a basic helix-loop-helix protein that forms a heterodimer with CLOCK. This heterodimer binds E-box enhancer elements upstream of Period (PER1, PER2, PER3) and Cryptochrome (CRY1, CRY2) genes and activates transcription of these genes. PER and CRY proteins heterodimerize and repress their own transcription by interacting in a feedback loop with CLOCK/ARNTL complexes. Defects in this gene have been linked to infertility, problems with gluconeogenesis and lipogenesis, and altered sleep patterns. Several transcript variants encoding different isoforms have been found for this gene.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human BMAL1 protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:WB 1:2000-1:10000

Calculated MW:69 kDa

ObservedMW:78 kDa