Recombinant beta III Tubulin Monoclonal Antibody

SKU: AN301935L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:beta III Tubulin

Target Synonym:FEOM;beta;CFEOM;CDCBM;CDCBM1;CFEOM3;CFEOM3A;FEOM3;TUBB4;beta-4;beta Tubulin III;TUBB3;beta 3 tubulin;M(beta)3;M(beta)6;MC1R;Neuron specific beta III Tubulin;Neuron-specific class III beta-tubulin;QccE-11995;QccE-15186;TBB3;Tubb 3;Tubulin beta 3;Tubulin beta 3 chain;Tubulin beta 4;Tubulin beta III;Tubulin beta-3 chain;Tubulin beta-4 chain;Tubulin beta-III

Research Areas:Neuroscience;Signal Transduction;Tags & Cell Markers

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Rat;Mouse

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A651

UNIProt ID:Q13509

Accession:

Background:Beta III Tubulin (TUBB3) is one of six β-tubulin isoforms and is expressed highly during fetal and postnatal development (axon guidance and maturation). Its expression levels decrease in the adult central nervous system (CNS) but remain high in the peripheral nervous system (PNS). Microtubules enriched in β3-tubulin are more dynamic than those composed of other β-tubulin isoforms. Research studies have shown that mutations in the β3-tubulin gene TUBB3 cause ocular motility defects and other nervous system disorders. Furthermore, β3-tubulin is present in neoplastic but not in normal differentiated glial cells. Thus, β3-tubulin is a great neuronal marker.

Concentration:1 mg/mL

Immunogen:Recombinant human beta III Tubulin fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:1000;IHC 1:200-1:1000

Calculated MW:50 kDa

ObservedMW:50 kDa