Recombinant B7-H3/CD276 Monoclonal Antibody

SKU: AN301442L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:B7-H3/CD276

Target Synonym:B7H;UNQ;PRO;B7-H;B7RP;B7 homolog;B7H34Ig-B7-H;PSEC;4Ig-B7-H;CD276;4Ig-B7-H3;B7-H3;B7H3;B7RP-2;B7 homolog 3;B7H34Ig-B7-H3;CD276 antigen;CD276 molecule;Costimulatory molecule;PSEC0249;UNQ309;PRO352;B7RP-2;4Ig-B7-H3;B7H3;B7-H3;CD276 antigen

Research Areas:Immunology;Cancer;Stem Cells

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse

Application:WB;IHC;IF;FCM;IP

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A137

UNIProt ID:Q5ZPR3

Accession:

Background:May participate in the regulation of T-cell-mediated immune response. May play a protective role in tumor cells by inhibiting natural-killer mediated cell lysis as well as a role of marker for detection of neuroblastoma cells. May be involved in the development of acute and chronic transplant rejection and in the regulation of lymphocytic activity at mucosal surfaces. Could also play a key role in providing the placenta and fetus with a suitable immunological environment throughout pregnancy. Both isoform 1 and isoform 2 appear to be redundant in their ability to modulate CD4 T-cell responses. Isoform 2 is shown to enhance the induction of cytotoxic T-cells and selectively stimulates interferon gamma production in the presence of T-cell receptor signaling.

Concentration:1 mg/mL

Immunogen:Recombinant human B7-H3/CD276 fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:500-1:2000;IHC 1:200-1:1000;IF 1:50;FCM 1:50-1:100;IP 1:25-1:100

Calculated MW:57 kDa

ObservedMW:110 kDa