Recombinant β Catenin Monoclonal Antibody

SKU: AN300903L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:β Catenin

Target Synonym:MRD;PRO;Catenin beta;SW-cl;OK/SW-cl;CTNNB;MRD19;armadillo;beta Catenin;CTNNB1;Beta-catenin;Catenin beta-1;OK;SW-cl.35;OK/SW-cl.35;PRO2286;88kDa;beta 1;Cadherin associated protein;Catenin (cadherin associated protein);Catenin beta 1;CATNB;CHBCAT;CTNB1;DKFZp686D02253;FLJ25606;FLJ37923;OTTHUMP00000162082;OTTHUMP00000165222;OTTHUMP00000165223;OTTHUMP00000209288;OTTHUMP00000209289;Catenin-β

Research Areas:Signal Transduction;Neuroscience;Stem Cells;Cancer;Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:8C4

UNIProt ID:P35222

Accession:

Background:The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Alternative splicing results in multiple transcript variants.

Concentration:0.2 mg/mL

Immunogen:Recombinant Human β Catenin protein

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A

Dilution:IHC 1:1000-1:5000;WB 1:1000-1:5000

Calculated MW:84 kDa

ObservedMW:96 kDa