Recombinant alpha-Galactosidase A/GLA Monoclonal Antibody

SKU: AN300412P

Size::20μL

Storage:This antibody can be stored at 2℃-8℃ for one month without detectable loss of activity. Antibody products are stable for twelve months from date of receipt when stored at -20℃ to -80℃. Preservative-Free. Avoid repeated freeze-thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Recombinant Antibodies;Monoclonal Antibodies

Abbreviation:GLA

Target Synonym:GLA;GALA;Alpha-D-Galactoside;Galactohydrolase;galactosidase alpha;GLAL;Melibiase;Agalsidase;Alpha-galactosidase A;Alpha-D-galactosidase A;Alpha-D-galactoside galactohydrolase;Galactosylgalactosylglucosylceramidase GLA

Research Areas:Cardiovascular

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human

Application:WB

Isotype:IgG

Clonality:Monoclonal

Clone NO.:5D11

UNIProt ID:P06280

Accession:

Background:alpha -Galactosidase A is a homodimeric glycoprotein that can release terminal alpha -galactosyl moieties from glycolipids and glycoproteins and catalyze the hydrolysis of melibiose into galactose and glucose . It is a lysosomal enzyme and is responsible for degradation of glycolipid globotriaosylceramide (Gb3) (Gal alpha 1‑4Gal beta 1‑4Glc beta ‑ceramide). Mutations in this gene cause Fabry disease, an X-linked hereditary lysosomal storage disease with the accumulation of Gb3 in the walls of small blood vessels, nerves, dorsal root ganglia, renal glomerular and tubular epithelial cells, and cardiomyocytes .

Concentration:1 mg/mL

Immunogen:Recombinant Human alpha-Galactosidase A/GLA protein

Buffer:0.2 μm filtered solution in PBS

Purification method:Protein A

Dilution:WB 1:500-1:2000

Calculated MW:49 kDa

ObservedMW:49 kDa