Recombinant AACT Monoclonal Antibody

SKU: AN301913L

Size::50μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Monoclonal Antibodies;Recombinant Antibodies

Abbreviation:AACT

Target Synonym:MGC;SERPINA;Serpin A;GIG;SERPINA3;AACT;ACT;GIG24;GIG25;Alpha-1-Antichymotrypsin;Cell Growth-Inhibiting Gene 24/25 Protein;MGC88254;Serpin A3;Alpha-1-antichymotrypsin His-Pro-less;Antichymotrypsin;antitrypsin) member 3;Cell growth inhibiting gene 24/25 protein;Growth inhibiting protein 24;Growth inhibiting protein 25;Serine (or cysteine) proteinase inhibitor clade A (alpha 1 antiproteinase;Serine (or cysteine) proteinase inhibitor clade A member 3;Serine proteinase inhibitor clade A member 3;Serpin family A member 3;Serpin peptidase inhibitor clade A (alpha 1 antiproteinase antitrypsin) member 3

Research Areas:Neuroscience;Cardiovascular;Cell Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;

Application:WB;IHC

Isotype:IgG,κ

Clonality:Monoclonal;Recombinant

Clone NO.:A629

UNIProt ID:P01011

Accession:

Background:Alpha 1-antichymotrypsin (AACT), also known as Human SerpinA3, is a member of the serine protease inhibitor class, and is a plasma alpha globulin glycoprotein which increases in the blood during the inflammatory process. SerpinA3, is also an inhibitor of neutrophil cathepsin G, mast cell chymases and pancreatic chymotrypsin. SerpinA3 is produced primarily in the liver, and is identified as an acute-phase inflammatory protein. SerpinA3 deficiency has been associated with liver disease. SerpinA3 has also been implicated in the pathology of a number of devastating human diseases including chronic obstructive pulmonary disease (COPD), Parkinson's disease (PD), Alzheimer's disease (AD), Stroke, Cystic Fibrosis, Cerebral Haemorrhage and Multiple System Atrophy.

Concentration:1 mg/mL

Immunogen:Recombinant human AACT fragment

Buffer:PBS, 50% glycerol, 0.05% Proclin 300, 0.05% protein protectant.

Purification method:Protein A purified

Dilution:WB 1:5000-1:10000;IHC 1:50-1:100

Calculated MW:48 kDa

ObservedMW:55-70 kDa