RBM8A Rabbit Polyclonal Antibody

SKU: BT-AP04409

Size:100μL

Background:This gene encodes a protein with a conserved RNA-binding motif. The protein is found predominantly in the nucleus| although it is also present in the cytoplasm. It is preferentially associated with mRNAs produced by splicing| including both nuclear mRNAs and newly exported cytoplasmic mRNAs. It is thought that the protein remains associated with spliced mRNAs as a tag to indicate where introns had been present| thus coupling pre- and post-mRNA splicing events. Previously| it was thought that two genes encode this protein| RBM8A and RBM8B; it is now thought that the RBM8B locus is a pseudogene. There are two alternate translation start codons with this gene| which result in two forms of the protein. An allele mutation and a low-frequency noncoding single-nucleotide polymorphism (SNP) in this gene cause thrombocytopenia-absent radius (TAR) syndrome.

Research_area:Epigenetics and nuclear signaling

Target_protein:RBM8A

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:RBM8A

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):19140

UniProt accession:Human: Q9Y5S9; Mouse: Q9CWZ3; Rat: Q27W01

Synonyms:RBM8A

GeneID:Human: 9939; Mouse: 60365; Rat: 295284