Rat Ubia Prenyltransferase Domain-containing Protein 1, UBIAD1 ELISA Kit

SKU: E2311Ra

Size:96 Tests-1 Kit

Background:Prenyltransferase that mediates the formation of menaquinone-4 (MK-4) and coenzyme Q10. MK-4 is a vitamin K2 isoform required for endothelial cell development. Mediates the conversion of phylloquinone (PK) into MK-4, probably by cleaving the side chain of phylloquinone (PK) to release 2-methyl-1,4-naphthoquinone (menadione; K3) and then prenylating it with geranylgeranyl pyrophosphate (GGPP) to form MK-4. Also plays a role in cardiovascular development independently of MK-4 biosynthesis, by acting as a coenzyme Q10 biosynthetic enzyme: coenzyme Q10, also named ubiquinone, plays an important antioxidant role in the cardiovascular system. Mediates biosynthesis of coenzyme Q10 in the Golgi membrane, leading to protect cardiovascular tissues from NOS3/eNOS-dependent oxidative stress (By similarity).

Research_area:Others

Applications:ELISA

Target_protein:UBIAD1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:9.36ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:UbiA prenyltransferase domain-containing protein 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:D3ZG27

MASS(Da):37,026

GeneID:313706

Synonyms:RGD1309588;UbiA prenyltransferase domain-containing protein 1;UBIAD1

Gene names:Ubiad1

Standard solution:4800ng/L