Rat soluble Interleukin-1 receptor type 1,sIL-1R1 ELISA KIT

SKU: E0120Ra

Size:96 Tests-1 Kit

Background:Receptor for IL1A, IL1B and IL1RN. After binding to interleukin-1 associates with the coreceptor IL1RAP to form the high affinity interleukin-1 receptor complex which mediates interleukin-1-dependent activation of NF-kappa-B, MAPK and other pathways. Signaling involves the recruitment of adapter molecules such as TOLLIP, MYD88, and IRAK1 or IRAK2 via the respective TIR domains of the receptor/coreceptor subunits. Binds ligands with comparable affinity and binding of antagonist IL1RN prevents association with IL1RAP to form a signaling complex. Involved in IL1B-mediated costimulation of IFNG production from T-helper 1 (Th1) cells (By similarity). {ECO:0000250|UniProtKB:P14778}.

Research_area:

Applications:ELISA

Target_protein:Il1r1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:38.29ng/L

Detection range:75-4800ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:soluble interleukin-1 receptor 1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q02955

MASS(Da):66759

GeneID:

Synonyms:Il1r1 Il1ra

Gene names:Il1r1

Standard solution:9600ng/L