Rat Sigma-1 receptor,SIGMAR1 ELISA KIT

SKU: E2108Ra

Size:96 Tests-1 Kit

Background:Functions in lipid transport from the endoplasmic reticulum and is involved in a wide array of cellular functions probably through regulation of the biogenesis of lipid microdomains at the plasma membrane. Involved in the regulation of different receptors it plays a role in BDNF signaling and EGF signaling. Also regulates ion channels like the potassium channel and could modulate neurotransmitter release. Plays a role in calcium signaling through modulation together with ANK2 of the ITP3R-dependent calcium efflux at the endoplasmic reticulum. Plays a role in several other cell functions including proliferation, survival and death. Originally identified for its ability to bind various psychoactive drugs it is involved in learning processes, memory and mood alteration. Necessary for proper mitochondrial axonal transport in motor neurons, in particular the retrograde movement of mitochondria. Plays a role in protecting cells against oxidative stress-induced cell death via its interaction with RNF112 (By similarity). {ECO:0000250|UniProtKB:O55242, ECO:0000269|PubMed:11861817, ECO:0000269|PubMed:11988171, ECO:0000269|PubMed:15170821, ECO:0000269|PubMed:15466698, ECO:0000269|PubMed:16522641, ECO:0000269|PubMed:9489711}.

Research_area:

Applications:ELISA

Target_protein:Sigmar1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.01ng/ml

Detection range:0.05-15ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Sigma-1 receptor

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q9R0C9

MASS(Da):25270

GeneID:29336

Synonyms:Sigmar1 Oprs1

Gene names:Sigmar1

Standard solution:16ng/ml