Rat PCSK9 ELISA Kit PicoKine®

SKU: EK1701

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: Pcsk9

Specificity: Natural and recombinant rat PCSK9

Background: PCSK9 is the 9th member of the proprotein convertase family of proteins that activate other proteins.PCSK9 has medical importance because it acts in lipoprotein homeostasis. PCSK9 is ubiquitously expressed in many tissues and cell types. PCSK9 binds to the receptor for low-density lipoprotein particles (LDL), which typically transport 3,000 to 6,000 fat molecules (including cholesterol) per particle, within extracellular fluid. The LDL receptor (LDLR), on liver and other cell membranes, binds and initiates ingestion of LDL-particles from extracellular fluid into cells, thus reducing LDL particle concentrations.

Immunogen: Expression system for standard: NS0; Immunogen sequence: S156-Q694

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Reference:

Uniprot ID: P59996

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 298296

Protein Name: Proprotein convertase subtilisin/kexin type 9

Gene Full Name: proprotein convertase subtilisin/kexin type 9

Synonyms: FH3; HCHOLA3; LDLCQ1; NARC 1; NARC1; PC9; PCSK9; Proprotein convertase 9