Rat Matrix Metallopeptidase 8, Neutrophil Collagenase, MMP8 ELISA Kit

SKU: E2143Ra

Size:96 Tests-1 Kit

Background:Neutrophil collagenase, also known as matrix metalloproteinase-8 (MMP-8) or PMNL collagenase (MNL-CL), is a collagen cleaving enzyme which is present in the connective tissue of most mammals. In humans, the MMP-8 protein is encoded by the MMP8 gene. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. However, the enzyme encoded by this gene is stored in secondary granules within neutrophils and is activated by autolytic cleavage.

Research_area:Cardiovascular

Applications:ELISA

Target_protein:MMP8

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.046ng/mL

Detection range:0.1-40ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:matrix metallopeptidase 8,neutrophil collagenase

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:O88766

MASS(Da):53,277

GeneID:63849

Synonyms:Matrix Metalloproteinase-8;MMP8;MMP-8;Neutrophil collagenase

Gene names:Mmp8

Standard solution:48ng/mL