Rat Formin-binding protein 1-like,FNBP1L ELISA KIT

SKU: E0982Ra

Size:96 Tests-1 Kit

Background:Required to coordinate membrane tubulation with reorganization of the actin cytoskeleton during endocytosis. May bind to lipids such as phosphatidylinositol 4,5-bisphosphate and phosphatidylserine and promote membrane invagination and the formation of tubules. Also promotes CDC42-induced actin polymerization by activating the WASL-WASPIP complex, the predominant form of WASL/N-WASP in cells. Actin polymerization may promote the fission of membrane tubules to form endocytic vesicles. Essential for autophagy of intracellular bacterial pathogens (By similarity). May negatively regulate neurite extension and axon branching in developing neurons. {ECO:0000250, ECO:0000269|PubMed:16885158}.

Research_area:

Applications:ELISA

Target_protein:Fnbp1l

Reactivity:Rat

Assay type:Sandwich

Sensitivity:46.95pg/ml

Detection range:100-6400pg/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Formin-binding protein 1-like

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q2HWF0

MASS(Da):69974

GeneID:310839

Synonyms:Fnbp1l Toca1

Gene names:Fnbp1l

Standard solution:12800pg/ml