Rat CPE/Carboxypeptidase E ELISA Kit PicoKine®

SKU: EK1889

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: Cpe

Specificity: Natural and recombinant rat CPE

Background: CPE may play a role in post-translational processing of peptide hormones including preproopiomelanocortin. It is mapped to 16p13.This gene encodes a member of the M14 family of metallocarboxypeptidases. The encoded preproprotein is proteolytically processed to generate the mature peptidase. This peripheral membrane protein cleaves C-terminal amino acid residues and is involved in the biosynthesis of peptide hormones and neurotransmitters, including insulin. This protein may also function independently of its peptidase activity, as a neurotrophic factor that promotes neuronal survival, and as a sorting receptor that binds to regulated secretory pathway proteins, including prohormones. Mutations in this gene are implicated in type 2 diabetes.

Immunogen: Expression system for standard: NS0; Immunogen sequence: L43-F476

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Reconstitution:

Reference:

Uniprot ID: P15087

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Conjugate:

Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

Isotype:

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Gene ID: 25669

Protein Name: Carboxypeptidase E

Gene Full Name: carboxypeptidase E

Synonyms: Carboxypeptidase E; Carboxypeptidase H; CPE; CPH; Enkephalin convertase