Rat Contactin-1, CNTN1 ELISA Kit

SKU: E1927Ra

Size:96 Tests-1 Kit

Background:Contactins mediate cell surface interactions during nervous system development. Involved in the formation of paranodal axo-glial junctions in myelinated peripheral nerves and in the signaling between axons and myelinating glial cells via its association with CNTNAP1. Participates in oligodendrocytes generation by acting as a ligand of NOTCH1. Its association with NOTCH1 promotes NOTCH1 activation through the released notch intracellular domain (NICD) and subsequent translocation to the nucleus. Interaction with TNR induces a repulsion of neurons and an inhibition of neurite outgrowth.

Research_area:Neuroscience

Applications:ELISA

Target_protein:CNTN1

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.048ng/mL

Detection range:0.1-40ng/mL

Sample type:Serum, plasma or other biological fluids

Full product name:Contactin-1

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q63198

MASS(Da):113,495

GeneID:117258

Synonyms:CNTN 1;CNTN1;Contactin 1;Contactin-1;Neural cell surface protein F3

Gene names:CNTN1

Standard solution:48ng/mL