Rat CNTF ELISA Kit PicoKine®

SKU: EK0324

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: CNTF

Specificity: Natural and recombinant rat CNTF

Background: Ciliary neurotrophic factor (CNTF) is a potent polypeptide hormone whose actions appear to be restricted to the nervous system where it promotes survival, neurotransmitter synthesis and neurite outgrowth in certain neuronal populations. The hCNTF gene is located on chromosome 11, as determined using human-hamster somatic cell hybrids. The CNTF protein is highly conserved in evolution. The amino acid (aa) sequences of rat and rabbit CNTF translated from cDNAs display approx. 85% homology with the deduced aa sequence encoding hCNTF. CNTF induces weight loss and improves glucose tolerance in humans and rodents. CNTF is thought to act centrally by inducing hypothalamic neurogenesis to modulate food intake and peripherally by altering hepatic gene expression, in a manner similar to that of leptin.

Immunogen: Expression system for standard: E.coli; Immunogen sequence: A2-M200

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Uniprot ID: P20294

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 25707

Protein Name: Ciliary neurotrophic factor

Gene Full Name: ciliary neurotrophic factor

Synonyms: ciliary neurotrophic factor; CNTF; HCNTF