Rat cluster of differentiation 14,CD14 ELISA KIT

SKU: E2491Ra

Size:96 Tests-1 Kit

Background:Coreceptor for bacterial lipopolysaccharide. In concert with LBP, binds to monomeric lipopolysaccharide and delivers it to the LY96/TLR4 complex, thereby mediating the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Acts as a coreceptor for TLR2:TLR6 heterodimer in response to diacylated lipopeptides and for TLR2:TLR1 heterodimer in response to triacylated lipopeptides, these clusters trigger signaling from the cell surface and subsequently are targeted to the Golgi in a lipid-raft dependent pathway. Binds electronegative LDL (LDL(-)) and mediates the cytokine release induced by LDL(-) (By similarity). {ECO:0000250|UniProtKB:P08571, ECO:0000250|UniProtKB:P10810}.

Research_area:

Applications:ELISA

Target_protein:Cd14

Reactivity:Rat

Assay type:Sandwich

Sensitivity:0.64ng/ml

Detection range:1-380ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:cluster of differentiation 14

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q63691

MASS(Da):40054

GeneID:60350

Synonyms:Cd14

Gene names:Cd14

Standard solution:400ng/ml