Rat CCL4/MIP1β PicoKine® Quick ELISA Kit

SKU: FEK0939

Size: 96 wells/kit, with removable strips.

Storage: Store at 4℃ for 6 months, at -20℃ for 12 months. Avoid multiple freeze-thaw cycles (Ships with gel ice, can store for up to 3 days in room temperature. Freeze upon receiving.)

Form:

Reactivity: Rat

Applications: ELISA

Application Details:

Gene Name: CCL4

Specificity: Natural and recombinant rat CCL4

Background: Chemokine (C-C motif) ligand 4, also known as CCL4, is a protein which in mouse is encoded by the CCL4 gene. It is a CC chemokine with specificity for CCR5 receptors. It is a chemoattractant for natural killer cells, monocytes and a variety of other immune cells. CCL4 is a major HIV-suppressive factor produced by CD8+ T cells. Performing-low memory CD8+ T cells that normally synthesize MIP-1-beta. By analysis of somatic cell hybrids and by in situ hybridization, the CCL4 gene was assigned to 17q21-q23. Based on functional analysis of MIP-1beta, one or more additional beta chemokine receptors that transduce MIP-1beta signals must also exist. MIP-1alpha and MIP-1beta have been shown to lack affinity for the erythrocyte surface chemokine receptor/Duffy antigen that binds many alpha as well as beta chemokines (11, 14).

Immunogen: Expression system for standard: E.coli; Immunogen sequence: A24-N92

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Reference:

Uniprot ID: P50230

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Cross Reactivity: There is no detectable cross-reactivity with other relevant proteins.

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Gene ID: 116637

Protein Name: C-C motif chemokine 4

Gene Full Name: C-C motif chemokine ligand 4

Synonyms: ACT 2; ACT2; CCL4; MIP 1 beta; HC21; LAG-1; MIP1B; SCYA4; G-26; LAG1; SCYA2; SCYA4; MIP1B1; AT744.1; MIP-1-beta