Rat Alpha-ketoglutarate dehy-drogenase,OGDH ELISA KIT

SKU: E2329Ra

Size:96 Tests-1 Kit

Background:2-oxoglutarate dehydrogenase (E1) component of the 2-oxoglutarate dehydrogenase complex (OGDHC), which mediates the decarboxylation of alpha-ketoglutarate (PubMed:18783430). The 2-oxoglutarate dehydrogenase complex catalyzes the overall conversion of 2-oxoglutarate to succinyl-CoA and CO(2) (Probable). The 2-oxoglutarate dehydrogenase complex is mainly active in the mitochondrion. A fraction of the 2-oxoglutarate dehydrogenase complex also localizes in the nucleus and is required for lysine succinylation of histones: associates with KAT2A on chromatin and provides succinyl-CoA to histone succinyltransferase KAT2A. {ECO:0000250|UniProtKB:Q02218, ECO:0000305|PubMed:18783430}.

Research_area:

Applications:ELISA

Target_protein:Ogdh

Reactivity:Rat

Assay type:Sandwich

Sensitivity:9.93ng/L

Detection range:20-4500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:α-ketoglutarate dehy-drogenase

Species:Rat

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:Q5XI78

MASS(Da):116296

GeneID:360975

Synonyms:Ogdh Ogdhl

Gene names:Ogdh

Standard solution:4800ng/L