RARB Antibody - Cat. #: CSB-PA127878

SKU: CSB-PA127878

Size :100ul

Clone Number:

Aliases:HAP antibody; HBV-activated protein antibody; NR1B2 antibody; Nuclear receptor subfamily 1 group B member 2 antibody; RAR B antibody; RAR beta antibody; RAR epsilon antibody; RAR-beta antibody; RAR-epsilon antibody; RARB antibody; RARB_HUMAN antibody; Retinoic acid receptor beta 2 antibody; Retinoic acid receptor beta 4 antibody; Retinoic acid receptor beta 5 antibody; Retinoic acid receptor beta antibody; Retinoic acid receptor beta polypeptide antibody; RRB2 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P10826

Immunogen:Synthesized peptide derived from Human Retinoic Acid Receptor ?.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Receptor for retinoic acid. Retinoic acid receptors bind as heterodimers to their target response elements in response to their ligands, all-trans or 9-cis retinoic acid, and regulate gene expression in various biological processes. The RXR/RAR heterodimers bind to the retinoic acid response elements (RARE) composed of tandem 5'-AGGTCA-3' sites known as DR1-DR5. In the absence or presence of hormone ligand, acts mainly as an activator of gene expression due to weak binding to corepressors. In concert with RARG, required for skeletal growth, matrix homeostasis and growth plate function.

Reuben Lotan, N. Engl. J. Med., May 1995; 332: 1405 - 1411.
Andrew Yen, Mol. Pharmacol., Dec 2004; 66: 1727 - 1737.
K Swisshelm, Cell Growth Differ., Feb 1994; 5: 133.
F Aoudjit, Cell Growth Differ., May 1995; 6: 515.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RARB

Research Areas:Epigenetics and Nuclear Signaling;Cancer;Signal transduction