RAD50 Antibody - Cat. #: CSB-PA967370

SKU: CSB-PA967370

Size :50ul

Clone Number:

Aliases:DNA repair protein RAD50 antibody; hRAD50 antibody; hsRAD50 antibody; Mrell antibody; NBSLD antibody; Rad 50 antibody; RAD50 2 antibody; rad50 antibody; RAD50 homolog (S cerevisiae) antibody; RAD50 homolog antibody; RAD50 PEN antibody; RAD50, S. cerevisiae, homolog of antibody; RAD50_HUMAN antibody; RAD502 antibody; Rad50l antibody; Truncated RAD50 protein antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q92878

Immunogen:Synthetic peptide of Human RAD50

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB; ELISA:1:2000-1:10000, WB:1:1000-1:5000

Background:The protein encoded by this gene is highly similar to Saccharomyces cerevisiae Rad50, a protein involved in DNA double-strand break repair. This protein forms a complex with MRE11 and NBS1. The protein complex binds to DNA and displays numerous enzymatic activities that are required for nonhomologous joining of DNA ends. This protein, cooperating with its partners, is important for DNA double-strand break repair, cell cycle checkpoint activation, telomere maintenance, and meiotic recombination. Knockout studies of the mouse homolog suggest this gene is essential for cell growth and viability. Mutations in this gene are the cause of Nijmegen breakage syndrome-like disorder.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen affinity purification

Conjugate:Non-conjugated

Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAD50

Research Areas:Epigenetics and Nuclear Signaling