RACGAP1 Antibody, FITC conjugated - Cat. #: CSB-PA884432LC01HU

SKU: CSB-PA884432LC01HU

Size :50ug

Clone Number:

Aliases:CYK4 antibody; GAP antibody; Gap1 antibody; GTPase activating protein antibody; HsCYK-4 antibody; ID GAP antibody; KIAA1478 antibody; Male germ cell RacGap antibody; MgcRacGAP antibody; Protein CYK4 homolg antibody; Protein CYK4 homolog antibody; Rac GTPase activating protein 1 antibody; Rac GTPase-activating protein 1 antibody; RACGAP 1 antibody; Racgap1 antibody; RGAP1_HUMAN antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q9H0H5

Immunogen:Recombinant Human Rac GTPase-activating protein 1 protein (86-331AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:

Background:Component of the centralspindlin complex that serves as a microtubule-dependent and Rho-mediated signaling required for the myosin contractile ring formation during the cell cycle cytokinesis. Required for proper attachment of the midbody to the cell membrane during cytokinesis. Plays key roles in controlling cell growth and differentiation of hematopoietic cells through mechanisms other than regulating Rac GTPase activity. Also involved in the regulation of growth-related processes in adipocytes and myoblasts. May be involved in regulating spermatogenesis and in the RACGAP1 pathway in neuronal proliferation. Shows strong GAP (GTPase activation) activity towards CDC42 and RAC1 and less towards RHOA. Essential for the early stages of embryogenesis. May play a role in regulating cortical activity through RHOA during cytokinesis. May participate in the regulation of sulfate transport in male germ cells.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:FITC

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RACGAP1

Research Areas:Cell biology; Signal transduction