Rabbit Ryanodine receptor 1,RyR1 ELISA KIT

SKU: E0068Rb

Size:96 Tests-1 Kit

Background:Calcium channel that mediates the release of Ca(2+) from the sarcoplasmic reticulum into the cytoplasm and thereby plays a key role in triggering muscle contraction following depolarization of T-tubules (PubMed:3722165, PubMed:10388749, PubMed:10097181, PubMed:12732639, PubMed:22036948, PubMed:26245150, PubMed:27662087). Repeated very high-level exercise increases the open probability of the channel and leads to Ca(2+) leaking into the cytoplasm (By similarity). Can also mediate the release of Ca(2+) from intracellular stores in neurons, and may thereby promote prolonged Ca(2+) signaling in the brain. Required for normal embryonic development of muscle fibers and skeletal muscle. Required for normal heart morphogenesis, skin development and ossification during embryogenesis (By similarity). {ECO:0000250|UniProtKB:E9PZQ0, ECO:0000269|PubMed:10388749, ECO:0000269|PubMed:12732639, ECO:0000269|PubMed:22036948, ECO:0000269|PubMed:27662087, ECO:0000305|PubMed:10097181, ECO:0000305|PubMed:26245150, ECO:0000305|PubMed:3722165}.

Research_area:

Applications:ELISA

Target_protein:RYR1

Reactivity:Rabbit

Assay type:Sandwich

Sensitivity:0.09ng/ml

Detection range:0.19-12ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:Ryanodine receptor 1

Species:Rabbit

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P11716

MASS(Da):565253

GeneID:100009540

Synonyms:RYR1

Gene names:RYR1

Standard solution:24ng/ml