RAB7B Antibody, Biotin conjugated - Cat. #: CSB-PA019220LD01HU

SKU: CSB-PA019220LD01HU

Size :50ug

Clone Number:

Aliases:MGC16212 antibody; MGC9726 antibody; RAB7 antibody; rab7B antibody; RAB7B; member RAS oncogene family antibody; RAB7B_HUMAN antibody; Ras related protein Rab 7b antibody; Ras-related protein Rab-7B antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q96AH8

Immunogen:Recombinant Human Ras-related protein Rab-7b protein (100-199AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Controls vesicular trafficking from endosomes to the trans-Golgi network (TGN). Acts as a negative regulator of TLR9 signaling and can suppress TLR9-triggered TNFA, IL6, and IFNB production in macrophages by promoting TLR9 lysosomal degradation. Also negatively regulates TLR4 signaling in macrophages by promoting lysosomal degradation of TLR4. Promotes megakaryocytic differentiation by increasing NF-kappa-B-dependent IL6 production and subsequently enhancing the association of STAT3 with GATA1. Not involved in the regulation of the EGF- and EGFR degradation pathway.

Clonality:Polyclonal

Isotype:IgG

Purification Method:>95%, Protein G purified

Conjugate:Biotin

Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, pH 7.4

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RAB7B

Research Areas:Tags & Cell Markers; Signal transduction