Purified Anti-Mouse CD107a Antibody[1D4B]

SKU: GBS-F1254A

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD107a

Target Synonym:LGP;lysosomal membrane glycoprotein;Lysosome-associated membrane glycoprotein;120 kDa lysosomal membrane glycoprotein;CD107 antigen-like family member A;CD107a;LGP-120;LGP-A;lysosomal membrane glycoprotein 1;Lysosomal membrane glycoprotein A;Lysosome-associated membrane glycoprotein 1;lysosome-associated membrane protein 1;P2B;Lamp-1;Lamp1; LGP-120

Research Areas:

Conjugation:Unconjugated

Host:Rat

Species reactivity:Mouse

Application:FCM

Usage:

Isotype:Rat IgG2a, κ

Clonality:Monoclonal

Clone NO.:1D4B

UNIProt ID:P11438

Background:CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Mouse CD107a protein

Buffer:PBS, pH 7.2. Contains 0.05% proclin 300.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:16783