Purified Anti-Human TNF-α Antibody[Adalimumab297.rMAb]

SKU: AN007900P

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:TNF-α

Target Synonym:Tumor Necrosis Factor Ligand Superfamily Member;TNFSF;TNF;DIF;TNF-alpha;TNFA;TNFSF2;TNLG1F;TNF alpha;Cachectin;Tumor Necrosis Factor;Tumor Necrosis Factor Ligand Superfamily Member 2;TNF-a;APC1;APC1 protein;DIF、TNF-alpha、TNFA、TNFSF2;Differentiation inducing factor;Macrophage cytotoxic factor;macrophage derived;member 2;Membrane Form;monocyte derived;soluble form;sTNFA;TNF superfamily;Tumor necrosis factor alpha

Research Areas:Immunology;Signal Transduction;Cancer;Cardiovascular;Metabolism

Conjugation:Unconjugated

Host:Human

Species reactivity:Human

Application:FCM

Usage:

Isotype:Human IgG1,κ

Clonality:Monoclonal

Clone NO.:Adalimumab297.rMAb

UNIProt ID:P01375

Background:This gene encodes a multifunctional proinflammatory cytokine that belongs to the tumor necrosis factor (TNF) superfamily. This cytokine is mainly secreted by macrophages. It can bind to, and thus functions through its receptors TNFRSF1A/TNFR1 and TNFRSF1B/TNFBR. This cytokine is involved in the regulation of a wide spectrum of biological processes including cell prolifeRation, differentiation, apoptosis, lipid metabolism, and coagulation. This cytokine has been implicated in a variety of diseases, including autoimmune diseases, insulin resistance, and cancer. Knockout studies in mice also suggested the neuroprotective function of this cytokine.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human TNF-alpha protein

Buffer:PBS, pH 7.2. Contains 0.05% proclin 300.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:7124