Purified Anti-Human CD61 Antibody[HIP11]

SKU: AN007990P

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD61

Target Synonym:ITGB;BDPLT16;BDPLT2;CD61;GP3A;GPIIIa;GT;Integrin beta 3;ITGB3;Integrin beta-3; &beta-3 integrin-n;beta subunit;CD 61;CD61 antigen;HPA 1;HPA 4;Integrin beta 3 (platelet glycoprotein IIIa antigen CD61);Integrin beta chain beta 3;ITB3;ITG B3;ITGB 3;ITG-B3;NAIT;Platelet fibrinogen receptor;Platelet fibrinogen receptor beta subunit;Platelet glycoprotein IIIa;Platelet glycoprotein IIIa precursor;Platelet Membrane Glycoprotein IIIa;PTP

Research Areas:Cardiovascular;Signal Transduction;Immunology;Stem Cells

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG1,κ

Clonality:Monoclonal

Clone NO.:HIP11

UNIProt ID:P05106

Background:CD61, also known as integrin β3 and glycoprotein IIIa (gpIIIa), is a 90 kD type I integral transmembrane glycoprotein. It is a member of the integrin family, associating with platelet gpIIb (CD41) to form CD41/CD61 complex and with integrin αV (CD51) to form αV/β3 (CD51/CD61) integrin. CD41/CD61 is expressed on platelets and megakaryocytes, and plays a role in platelet activation and aggregation through interaction with fibrinogen, fibronectin, vWF, and other RGD-containing adhesion molecules. CD51/CD61 is expressed on platelets, osteoclasts, fibroblasts, macrophages, and some tumor cells involved in tumor metastasis, and in adenovirus infection through binding to RGD motif in extracellular matrix proteins.

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD61 protein

Buffer:PBS, pH 7.2. Contains 0.05% proclin 300.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID: