Purified Anti-Human CD123 Antibody[7G3]

SKU: AN002850P

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD123

Target Synonym:IL3RA;CD123;IL3R;IL3RAY;IL3RX;IL3RY;hIL-3Ra;IL-3 Receptor alpha;IL-3 receptor subunit alpha;IL-3R subunit alpha;IL-3R subunitalpha;IL-3RA;IL-3R-alpha;IL-3Receptoralpha;IL-3Rα;IL-4Receptoralpha;IL-5Receptoralpha;IL-6Receptoralpha;IL-7Receptoralpha;Interleukin-3 receptor subunit alpha;IL-3R&alpha

Research Areas:Immunology;Signal Transduction

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG2a, κ

Clonality:Monoclonal

Clone NO.:7G3

UNIProt ID:P26951

Background:CD123 is the 70 kD transmembrane α chain of the IL-3 receptor. Alone, CD123 binds IL-3 with low affinity; when CD123 associates with CDw131 (common β chain), it binds IL-3 with high affinity. CD123 does not transduce intracellular signals upon binding IL-3 and requires the β chain for this function. CD123 is expressed by myeloid precursors, macrophages, dendritic cells, mast cells, basophils, megakaryocytes, and some B cells.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD123 protein

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:3563