Purified Anti-Human CD11c Antibody[BU15]

SKU: GBS-F11180P

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD11c

Target Synonym:SLEB;Leukocyte adhesion receptor p150+;ITGAX;CD11C;SLEB6;CD11 antigen-like family member C;Integrin alpha-X;Leukocyte adhesion receptor p150+95;p150-95; CR4; integrin &alpha-X-X

Research Areas:Signal Transduction;Immunology;Stem Cells

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:

Isotype:Mouse IgG1,κ

Clonality:Monoclonal

Clone NO.:BU15

UNIProt ID:P20702

Background:This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. Two transcript variants encoding different isoforms have been found for this gene.

Concentration: ≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD11c protein

Buffer:Phosphate-buffered solution, pH 7.2, containing 0.05% non-protein stabilizer. Dialyze to completely remove the stabilizer prior to labeling.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:3687