Purified Anti-Human CD11a Antibody[R7-1]

SKU: GBS-F1211A

Size:1mg

Storage:Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.

Shipping:Ice bag

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Flow Cytometry Antibodies

Abbreviation:CD11a

Target Synonym:LFA;Lymphocyte antigen;CD11A;LFA-1;LFA1A;ITGAL;LFA-1A;Ly-15;Lymphocyte antigen 15;Integrin alpha-L;CD11 antigen-like family member A;Leukocyte adhesion glycoprotein LFA-1 alpha chain (LFA-1A);Leukocyte function-associated molecule 1 alpha chain; integrin &alpha-L-L;LFA1

Research Areas:Signal Transduction;Immunology;Stem Cells

Conjugation:Unconjugated

Host:Mouse

Species reactivity:Human

Application:FCM

Usage:Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 2.0 µg per 10⁶ cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Isotype:Mouse IgG1,κ

Clonality:Monoclonal

Clone NO.:R7-1

UNIProt ID:P20701

Background:CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Concentration:≥ 1 mg/mL

Control catalog number:

Immunogen:Recombinant Human CD11A protein

Buffer:PBS, pH 7.2. Contains 0.05% proclin 300.

Purification method:>98%, Protein A/G purified

Dilution:FCM 2 μg/mL(0.5×10⁶-1×10⁶ cells)

GeneID:3683