PTK7 Monoclonal Antibody

SKU: BT-MCA2160

Size:100μL

Background:Receptor protein tyrosine kinases transduce extracellular signals across the cell membrane. A subgroup of these kinases lack detectable catalytic tyrosine kinase activity but retain roles in signal transduction. The protein encoded by this gene is a member of this subgroup of tyrosine kinases and may function as a cell adhesion molecule. This gene is thought to be expressed in colon carcinomas but not in normal colon, and therefore may be a marker for or may be involved in tumor progression. Four transcript variants encoding four different isoforms have been found for this gene.Tissue specificity: Highly expressed in lung, liver, pancreas, kidney, placenta and melanocytes. Weakly expressed in thyroid gland, ovary, brain, heart and skeletal muscle. Also expressed in erythroleukemia cells. But not expressed in colon.

Research_area:Tags &amp, Cell Markers, Signal Transduction, Metabolism

Target_protein:PTK7

applications:WB, IHC

Reactivity:Human

Clonality:Monoclonal

Clone ID:4F9

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PTK7

Immunogen:Purified recombinant fragment of human PTK7 expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):118kDa

UniProt accession:Q13308

Synonyms:CCK4, PTK7

GeneID:5754