PTGES3 Antibody - Cat. #: CSB-PA613587ESR2HU

SKU: CSB-PA613587ESR2HU

Size :50ul

Clone Number:

Aliases:Co chaperone p23 antibody; cPGES antibody; Cytosolic prostaglandin E synthase antibody; Cytosolic prostaglandin E2 synthase antibody; Hsp90 co chaperone antibody; Hsp90 co-chaperone antibody; P23 antibody; Progesterone receptor complex antibody; Progesterone receptor complex p23 antibody; Prostaglandin E synthase 3 (cytosolic) antibody; Prostaglandin E synthase 3 antibody; PTGES 3 antibody; PTGES3 antibody; Sid 3177 antibody; TEBP antibody; TEBP_HUMAN antibody; Telomerase binding protein p23 antibody; Telomerase-binding protein p23 antibody; Unactive progesterone receptor 23 kD antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15185

Immunogen:Recombinant Human Prostaglandin E synthase 3 protein (1-110AA)

Raised in:Rabbit

Species Reactivity:Human

Tested Applications:ELISA

Background:Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2) (PubMed:10922363). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes (PubMed:11274138, PubMed:12077419). Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antigen Affinity Purified

Conjugate:Non-conjugated

Buffer:PBS with 0.02% sodium azide, 50% glycerol, pH7.3.

Form:Liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:PTGES3

Research Areas:Epigenetics and Nuclear Signaling; Cancer; Immunology; Metabolism; Signal transduction