PSMA6 Polyclonal Antibody

SKU: E-AB-53111

Size::120μL

Storage:Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping:The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date:12 months

Category ID_II:Primary Antibodies

Category ID_III:Polyclonal Antibodies

Abbreviation:PSMA6

Target Synonym:27 kDa prosomal protein;IOTA;Macropain iota chain;Macropain subunit iota;MGC22756;MGC2333;MGC23846;Multicatalytic endopeptidase complex iota chain;p27K;PROS 27;PROS-27;PROS27;Prosomal P27K protein;Proteasome (prosome macropain) subunit alpha type 6;Proteasome iota chain;Proteasome subunit alpha type 6;Proteasome subunit alpha type-6;Proteasome subunit iota;PSA6;PSMA 6;PSMA6

Research Areas:Cancer;Cell Biology

Conjugation:Unconjugated

Host:Rabbit

Species reactivity:Human;Mouse;Rat

Application:WB;IHC

Isotype:IgG

Clonality:Polyclonal

Clone NO.:

UNIProt ID:P60900

Accession:

Background:The proteasome is a multicatalytic proteinase complex with a highly ordered ring-shaped 20S core structure. The core structure is composed of 4 rings of 28 non-identical subunits; 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. This gene encodes a member of the peptidase T1A family, that is a 20S core alpha subunit. Multiple transcript variants encoding several different isoforms have been found for this gene. A pseudogene has been identified on the Y chromosome.

Concentration:1.14 mg/mL

Immunogen:Fusion protein of human PSMA6

Buffer:PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method:Antigen affinity purification

Dilution:WB 1:1000-1:5000;IHC 1:50-1:200

Calculated MW:27 kDa

ObservedMW:Refer to figures