PSA (KLK3) Monoclonal Antibody

SKU: BT-MCA2721

Size:100μL

Background:Kallikrein-related peptidase 3.Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Serum level of this protein, called PSA in the clinical setting, is useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Research_area:Others

Target_protein:PSA (KLK3)

applications:IHC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5A11E2

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PSA (KLK3)

Immunogen:Purified recombinant fragment of KLK3 (aa26-251) expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):

UniProt accession:P07288

Synonyms:APS, PSA, hK3, KLK2A1, KLK3

GeneID:354