PRGC2 Rabbit Polyclonal Antibody

SKU: BT-AP12191

Size:100μL

Background:The protein encoded by this gene stimulates the activity of several transcription factors and nuclear receptors| including estrogen receptor alpha| nuclear respiratory factor 1| and glucocorticoid receptor. The encoded protein may be involved in fat oxidation| non-oxidative glucose metabolism| and the regulation of energy expenditure. This protein is downregulated in prediabetic and type 2 diabetes mellitus patients. Certain allelic variations in this gene increase the risk of the development of obesity. Three transcript variants encoding different isoforms have been found for this gene.

Research_area:Cardiovascular; Epigenetics and nuclear signaling; Metabolism; Signal transduction

Target_protein:PPARGC1B

applications:WB

Reactivity:Human, Mouse, Rat

Clonality:Polyclonal

Clone ID:

Host:Rabbit

Isotype:IgG

Gene Symbol/ Name:PRGC2

Immunogen:The antiserum was produced against synthesized peptide derived from human AMPK alpha around the phosphorylation site of Thr172. AA range:140-189

Storage:-20°C for 1 year

Purification:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Formulation:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.

Concentration:1 mg/ml

Molecular weight(Da):112530

UniProt accession:Human: Q86YN6; Mouse: Q8VHJ7; Rat: Q811R2

Synonyms:PRGC2

GeneID:Human: 133522; Mouse: 170826; Rat: 291567