Prealbumin/transthyretin antibody , Cat. # FNab06761

SKU: FNab06761

Size:100ug

Purification:Protein A+G purification

Form:liquid

Purity:?95% as determined by SDS-PAGE

Host:Mouse

Clonality:monoclonal

Clone ID:8E4

Isotype:IgG1

Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.)

Background:Transthyretin(TTR) is a plasma transport protein for thyroxine and retinol, through the association with retinol-binding protein. It is a homotetrameric protein synthesized mainly in liver, choroid plexus, retinal pigment epithelium, and pancreas.Within the CNS, TTR is the only known protein synthesized solely by the choroid plexus. Mutant and wildtype TTR give rise to various forms of amyloid deposition(amyloidosis). Defects in TTR are the cause of amyloidosis transthyretin-related(AMYL-TTR),hyperthyroxinemia dystransthyretinemic euthyroidal(HTDE) and carpal tunnel syndrome type 1(CTS1). In addition, positive immunostaining for TTR has been reported as a sensitive diagnostic marker of choroid plexus tumors.(22103483)

Immunogen:transthyretin

Synonyms:ATTR, HsT2651, PALB, Prealbumin, TBPA, transthyretin, TTR

Observed MW:16kd

Uniprot ID:P02766

Reactivity:Human

Tested Application:ELISA, WB, IHC

Recommended dilution:WB: 1:500-1:5000; IHC: 1:20-1:200

Gene ID:7276

Research Area:Cancer, Immunology, Signal Transduction