PPY Polyclonal Antibody

SKU: E-AB-52056

Size: 200μL

Storage: Store at -20℃ Valid for 12 months. Avoid freeze / thaw cycles.

Shipping: The product is shipped with ice pack,upon receipt,store it immediately at the temperature recommended.

Exp date: 12 months

Category ID_II: Primary Antibodies

Category ID_III: Polyclonal Antibodies

Abbreviation: PPY

Target Synonym: Pancreatic polypeptide;Pancreatic polypeptide Y;Pancreatic prohormone;PNP;PP;PPY;prepro-PP (prepropancreatic polypeptide)

Research Areas: Cancer;Signal transduction

Conjugation: Unconjugated

Host: Rabbit

Species reactivity: Human;Rat

Application: WB

Isotype: IgG

Clonality: Polyclonal

Clone NO.:

UNIProt ID: P01298

Accession:

Background: This gene encodes a member of the neuropeptide Y (NPY) family of peptides. The encoded 95 aa preproprotein is synthesized in the pancreatic islets of Langerhans and proteolytically processed to generate two peptide products. These products include the active pancreatic hormone of 36 aa and an icosapeptide of unknown function. This hormone acts as a regulator of pancreatic and gastrointestinal functions and may be important in the regulation of food intake. Plasma level of this hormone has been shown to be reduced in conditions associated with increased food intake and elevated in anorexia nervosa. In addition, infusion of this hormone in obese rodents has shown to decrease weight gain. Alternative splicing results in multiple transcript variants, at least one of which encodes an isoform that is proteolytically processed.

Concentration: 2.28 mg/mL

Immunogen: Synthetic peptide of human PPY

Buffer: PBS with 0.05% NaN3 and 40% Glycerol,pH7.4

Purification method: Antigen affinity purification

Dilution: WB 1:1000-1:5000

Calculated MW: 11 kDa

ObservedMW: Refer to figures