Porcine Integrin beta-2,ITGB2 ELISA KIT

SKU: E0077Po

Size:96 Tests-1 Kit

Background:Integrin ITGAL/ITGB2 is a receptor for ICAM1, ICAM2, ICAM3 and ICAM4. Integrin ITGAL/ITGB2 is also a receptor for the secreted form of ubiquitin-like protein ISG15; the interaction is mediated by ITGAL. Integrins ITGAM/ITGB2 and ITGAX/ITGB2 are receptors for the iC3b fragment of the third complement component and for fibrinogen. Integrin ITGAX/ITGB2 recognizes the sequence G-P-R in fibrinogen alpha-chain. Integrin ITGAM/ITGB2 recognizes P1 and P2 peptides of fibrinogen gamma chain. Integrin ITGAM/ITGB2 is also a receptor for factor X. Integrin ITGAD/ITGB2 is a receptor for ICAM3 and VCAM1. Contributes to natural killer cell cytotoxicity. Involved in leukocyte adhesion and transmigration of leukocytes including T-cells and neutrophils. Triggers neutrophil transmigration during lung injury through PTK2B/PYK2-mediated activation. Integrin alpha-L/beta-2 in association with ICAM3, contributes to apoptotic neutrophil phagocytosis by macrophages. {ECO:0000250|UniProtKB:P05107}.

Research_area:

Applications:ELISA

Target_protein:ITGB2

Reactivity:Porcine

Assay type:Sandwich

Sensitivity:0.39ng/ml

Detection range:0.75-48ng/ml

Sample type:Serum, plasma or other biological fluids

Full product name:integrin β2

Species:Porcine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P53714

MASS(Da):84790

GeneID:396943

Synonyms:ITGB2 CD18

Gene names:ITGB2

Standard solution:96ng/ml