Porcine Atp Synthase Subunit Alpha, Mitochondrial, ATP5A1 ELISA Kit

SKU: E0530Po

Size:96 Tests-1 Kit

Background:Mitochondrial membrane ATP synthase (F1F0 ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F1 - containing the extramembraneous catalytic core, and F0 - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F1 is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Subunits alpha and beta form the catalytic core in F1. Rotation of the central stalk against the surrounding alpha3beta3 subunits leads to hydrolysis of ATP in three separate catalytic sites on the beta subunits. Subunit alpha does not bear the catalytic high-affinity ATP-binding sites (By similarity). Binds the bacterial siderophore enterobactin and can promote mitochondrial accumulation of enterobactin-derived iron ions (By similarity).

Research_area:Tags & Cell Markers; Signal Transduction; Metabolism

Applications:ELISA

Target_protein:ATP5A1

Reactivity:Porcine

Assay type:Sandwich

Sensitivity:9.52ng/L

Detection range:20-3500ng/L

Sample type:Serum, plasma or other biological fluids

Full product name:ATP Synthase subunit alpha, mitochondrial

Species:Porcine

Storage:2-8ºC

Assay time:1h 30m

UniProt accession:P80021

MASS(Da):59,688

GeneID:100157880

Synonyms:ATP Synthase F1 subunit alpha;ATP Synthase subunit alpha heart isoform, mitochondrial;ATP Synthase subunit alpha liver isoform, mitochondrial;ATP Synthase subunit alpha, mitochondrial;ATP5A1;ATP5A2

Gene names:ATP5F1A

Standard solution:4000ng/L