POLB Antibody - Cat. #: CSB-PA910465

SKU: CSB-PA910465

Size :100ul

Clone Number:

Aliases:DNA directed DNA polymerase beta antibody; DNA pol beta antibody; DNA polymerase beta antibody; DNA polymerase beta subunit antibody; DPOLB_HUMAN antibody; MGC125976 antibody; Pol B antibody; Pol beta antibody; POLB antibody; Polymerase (DNA directed) beta antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:P06746

Immunogen:Synthesized peptide derived from Human DNA Polymerase ?.

Raised in:Rabbit

Species Reactivity:Human, Mouse, Rat

Tested Applications:ELISA, WB, IHC; WB:1:500-1:3000, IHC:1:50-1:100

Background:Repair polymerase that plays a key role in base-excision repair. Has 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity that removes the 5' sugar phosphate and also acts as a DNA polymerase that adds one nucleotide to the 3' end of the arising single-nucleotide gap. Conducts 'gap-filling' DNA synthesis in a stepwise distributive fashion rather than in a processive fashion as for other DNA polymerases.

Hiroyuki Matsumoto, Plant Cell Physiol., Nov 1981; 22: 1317 - 1324.
L.K. Karagyozov, Nucleic Acids Res., Jun 1978; 5: 1907 - 1917.
F Costanzo, J. Virol., Mar 1977; 21: 996 - 1001.
AJ Faber, Eur. J. Biochem., Nov 1981; 120: 357.

Clonality:Polyclonal

Isotype:IgG

Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:POLB

Research Areas:Epigenetics and Nuclear Signaling