PIPK I γ rabbit pAb

SKU: ES3212

Size: 100μL

Source:Rabbit

Applications:WB;ELISA

Reactivity:Human;Rat;Mouse;

Dilution:Western Blot: 1/500 - 1/2000. ELISA: 1/20000. Not yet tested in other applications.

Immunogen:The antiserum was produced against synthesized peptide derived from human PIP5K1C. AA range:305-354

Storage_stability:-20°C/1 year

Clonality:Polyclonal

Isotype:IgG

Concentration:1 mg/ml

Observed_band(KD):80kD

Human_gene_id:23396

Human_swiss_prot_no:O60331

Subcellular_location:Cell membrane; Peripheral membrane protein; Cytoplasmic side . Endomembrane system . Cytoplasm . Cell junction, focal adhesion . Cell junction, adherens junction . Cell projection, ruffle membrane . Cell projection, phagocytic cup . Cell projection, uropodium . Detected in plasma membrane invaginations. Isoform 3 is detected in intracellular vesicle-like structures.; [Isoform 2]: Cytoplasm. Nucleus.

Other_name:PIP5K1C; KIAA0589; Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma; PIP5K1-gamma; PtdIns(4)P-5-kinase 1 gamma; Phosphatidylinositol 4-phosphate 5-kinase type I gamma; PIP5KIgamma

Background:phosphatidylinositol-4-phosphate 5-kinase type 1 gamma(PIP5K1C) Homo sapiens This locus encodes a type I phosphatidylinositol 4-phosphate 5-kinase. The encoded protein catalyzes phosphorylation of phosphatidylinositol 4-phosphate, producing phosphatidylinositol 4,5-bisphosphate. This enzyme is found at synapses and has been found to play roles in endocytosis and cell migration. Mutations at this locus have been associated with lethal congenital contractural syndrome. Alternatively spliced transcript variants encoding different isoforms have been described.[provided by RefSeq, Sep 2010],