PINCH Monoclonal Antibody

SKU: BT-MCA2461

Size:100μL

Background:The protein encoded by this gene is an adaptor protein which contains five LIM domains, or double zinc fingers. The protein is likely involved in integrin signaling through its LIM domain-mediated interaction with integrin-linked kinase, found in focal adhesion plaques. It is also thought to act as a bridge linking integrin-linked kinase to NCK adaptor protein 2, which is involved in growth factor receptor kinase signaling pathways. Its localization to the periphery of spreading cells also suggests that this protein may play a role in integrin-mediated cell adhesion or spreading. Several transcript variants encoding different isoforms have been found for this gene.

Research_area:Others

Target_protein:PINCH

applications:ICC, FCM

Reactivity:Human

Clonality:Monoclonal

Clone ID:5G7

Host:Mouse

Isotype:Mouse IgG1

Gene Symbol/ Name:PINCH

Immunogen:Purified recombinant fragment of human PINCH expressed in E. Coli.

Storage:4°C|-20°C for long term storage

Purification:

Formulation:Ascitic fluid containing 0.03% sodium azide.

Concentration:

Molecular weight(Da):37kDa

UniProt accession:P48059

Synonyms:PINCH, PINCH1, PINCH-1, LIMS1

GeneID:3987