Phospho-RPS6KA1/RPS6KA3/RPS6KA2/RPS6KA6 (Ser221/227/S218/232) Antibody - Cat. #: CSB-PA182506

SKU: CSB-PA182506

Size :100ul

Clone Number:

Aliases:90 kDa ribosomal protein S6 kinase 1 antibody; dJ590P13.1 (ribosomal protein S6 kinase; 90kD; polypeptide 1 antibody; dJ590P13.1 antibody; EC 2.7.11.1 antibody; HU 1 antibody; HU1 antibody; KS6A1_HUMAN antibody; MAP kinase activated protein kinase 1a antibody; MAP kinase-activated protein kinase 1a antibody; MAPK-activated protein kinase 1a antibody; MAPKAP kinase 1a antibody; MAPKAPK-1a antibody; MAPKAPK1A antibody; MGC79981 antibody; Mitogen-activated protein kinase-activated protein kinase 1A antibody; OTTHUMP00000004113 antibody; p90 RSK1 antibody; p90-RSK 1 antibody; p90rsk antibody; p90RSK1 antibody; p90S6K antibody; pp90RSK1 antibody; Ribosomal protein S6 kinase 90kD 1 antibody; Ribosomal protein S6 kinase 90kD polypeptide 1 antibody; Ribosomal protein S6 kinase 90kDa polypeptide 1 antibody; Ribosomal protein S6 kinase alpha 1 antibody; Ribosomal protein S6 kinase alpha-1 antibody; Ribosomal protein S6 kinase polypeptide 1 antibody; Ribosomal S6 kinase 1 antibody; RPS6K1 alpha antibody; rps6ka antibody; Rps6ka1 antibody; RSK 1 antibody; RSK 1 p90 antibody; RSK antibody; RSK-1 antibody; RSK1 antibody; RSK1p90 antibody; S6K alpha 1 antibody; S6K-alpha-1 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q15418

Immunogen:Peptide sequence around phosphorylation site of Serine 221/227/218/232(A-Y-S(p)-F-C) derived from Human RSK1/2/3/4.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB; WB:1:500-1:1000

Background:

This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 nonidentical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway. The activity of this protein has been implicated in controlling cell growth and differentiation. Alternate transcriptional splice variants, encoding different isoforms, have been characterized. This gene encodes a member of the RSK (ribosomal S6 kinase) family of serine/threonine kinases. This kinase contains 2 non-identical kinase catalytic domains and phosphorylates various substrates, including members of the mitogen-activated kinase (MAPK) signalling pathway.

Moller D.E., Am. J. Physiol. 266:C351-C359(1994).
Gregory S.G., Nature 441:315-321(2006).
The MGC Project Team, Genome Res. 14:2121-2127(2004).

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:RPS6KA1/RPS6KA3/RPS6KA2/RPS6KA6

Research Areas:Epigenetics and Nuclear Signaling;Signal transduction