1 1

Gene Bio Systems

Phospho-KCNJ11 (Thr224) Antibody - Cat. #: CSB-PA209100

Phospho-KCNJ11 (Thr224) Antibody - Cat. #: CSB-PA209100

CSB-PA209100

¥134,300 JPY
¥134,300 JPY
Sale Sold out
Shipping calculated at checkout.

Size :100ul

Clone Number:

Aliases:KCNJ11 antibody; ATP-sensitive inward rectifier potassium channel 11 antibody; IKATP antibody; Inward rectifier K(+) channel Kir6.2 antibody; Potassium channel antibody; inwardly rectifying subfamily J member 11 antibody

Product Type:Polyclonal Antibody

Immunogen Species:Homo sapiens (Human)

UniProt ID:Q14654

Immunogen:Peptide sequence around phosphorylation site of threonine 224 (K-T-TP-S-P) derived from Human Kir6.2.

Raised in:Rabbit

Species Reactivity:Human, Mouse

Tested Applications:ELISA, WB, IF; WB:1:500-1:1000, IF:1:100-1:200

Background:This receptor is controlled by G proteins. Inward rectifier potassium channels are characterized by a greater tendency to allow potassium to flow into the cell rather than out of it. Their voltage dependence is regulated by the concentration of extracellular potassium; as external potassium is raised, the voltage range of the channel opening shifts to more positive voltages. The inward rectification is mainly due to the blockage of outward current by internal magnesium. Can be blocked by extracellular barium By similarity. Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with ABCC9. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation.

Clonality:Polyclonal

Isotype:IgG

Purification Method:Antibodies were produced by immunizing rabbits with synthetic phosphopeptide and KLH conjugates. Antibodies were purified by affinity-chromatography using epitope-specific phosphopeptide. Non-phospho specific antibodies were removed by chromatogramphy usi

Conjugate:Non-conjugated

Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.

Form:liquid

Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze.

Target Names:KCNJ11

Research Areas:Neuroscience?Cancer?Cardiovascular;Metabolism;Signal transduction

View full details